Ligand id: 6452

Name: dipraglurant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 30.19
Molecular weight 265.1
XLogP 3.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Chae E, Shin YJ, Ryu EJ, Ji MK, Ryune Cho N, Lee KH, Jeong HJ, Kim SJ, Choi Y, Seok Oh K et al.. (2013)
Discovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators.
Bioorg. Med. Chem. Lett., 23 (7): 2134-9. [PMID:23434029]