trandolapril

Ligand id: 6453

Name: trandolapril

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 95.94
Molecular weight 430.25
XLogP 5.49
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

References
1. Chevillard C, Jouquey S, Bree F, Mathieu MN, Stepniewski JP, Tillement JP, Hamon G, Corvol P. (1994)
Compared properties of trandolapril, enalapril, and their diacid metabolites.
J. Cardiovasc. Pharmacol.23 Suppl 4: S11-5. [PMID:7527095]