compound 10 [PMID: 22533316]

Ligand id: 6717

Name: compound 10 [PMID: 22533316]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 70.08
Molecular weight 422.2
XLogP 3.86
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Staedler D, Chapuis-Bernasconi C, Dehmlow H, Fischer H, Juillerat-Jeanneret L, Aebi JD. (2012)
Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells.
J. Med. Chem.55 (11): 4990-5002. [PMID:22533316]