pimecrolimus

Ligand id: 6783

Name: pimecrolimus

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 158.13
Molecular weight 809.45
XLogP 4.42
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Hultsch T, Müller KD, Meingassner JG, Grassberger M, Schopf RE, Knop J. (1998)
Ascomycin macrolactam derivative SDZ ASM 981 inhibits the release of granule-associated mediators and of newly synthesized cytokines in RBL 2H3 mast cells in an immunophilin-dependent manner.
Arch. Dermatol. Res.290 (9): 501-7. [PMID:9808344]