finasteride

Ligand id: 6818

Name: finasteride

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 58.2
Molecular weight 372.28
XLogP 4.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Rasmusson GH, Reynolds GF, Steinberg NG, Walton E, Patel GF, Liang T, Cascieri MA, Cheung AH, Brooks JR, Berman C. (1986)
Azasteroids: structure-activity relationships for inhibition of 5 alpha-reductase and of androgen receptor binding.
J. Med. Chem.29 (11): 2298-315. [PMID:3783591]