ribavirin

Ligand id: 6842

Name: ribavirin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 3
Topological polar surface area 143.72
Molecular weight 244.08
XLogP -3.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Choi MK, Kim MH, Maeng HJ, Song IS. (2015)
Contribution of CNT1 and ENT1 to ribavirin uptake in human hepatocytes.
Arch. Pharm. Res.38 (5): 904-13. [PMID:25011570]
2. Wittine K, Stipković Babić M, Makuc D, Plavec J, Kraljević Pavelić S, Sedić M, Pavelić K, Leyssen P, Neyts J, Balzarini J et al.. (2012)
Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and imino-ascorbic acid: synthesis, anti-HCV and antitumor activity evaluations.
Bioorg. Med. Chem.20 (11): 3675-85. [PMID:22555152]