flutamide

Ligand id: 6943

Name: flutamide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 72.24
Molecular weight 276.07
XLogP 3.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Wakabayashi K, Imai K, Miyachi H, Hashimoto Y, Tanatani A. (2008)
4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor.
Bioorg. Med. Chem.16 (14): 6799-812. [PMID:18571420]