dextromethorphan

Ligand id: 6953

Name: dextromethorphan

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 12.47
Molecular weight 271.19
XLogP 4.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Dravid SM, Erreger K, Yuan H, Nicholson K, Le P, Lyuboslavsky P, Almonte A, Murray E, Mosely C, Barber J et al.. (2007)
Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.
J. Physiol. (Lond.)581 (Pt 1): 107-28. [PMID:17303642]
2. Ganapathy ME, Prasad PD, Huang W, Seth P, Leibach FH, Ganapathy V. (1999)
Molecular and ligand-binding characterization of the sigma-receptor in the Jurkat human T lymphocyte cell line.
J. Pharmacol. Exp. Ther.289 (1): 251-60. [PMID:10087012]
3. Kotzer CJ, Hay DW, Dondio G, Giardina G, Petrillo P, Underwood DC. (2000)
The antitussive activity of delta-opioid receptor stimulation in guinea pigs.
J. Pharmacol. Exp. Ther.292 (2): 803-9. [PMID:10640321]