chlorpheniramine

Ligand id: 6976

Name: chlorpheniramine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 16.13
Molecular weight 274.12
XLogP 4.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Procopiou PA, Browning C, Buckley JM, Clark KL, Fechner L, Gore PM, Hancock AP, Hodgson ST, Holmes DS, Kranz M et al.. (2011)
The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.
J. Med. Chem.54 (7): 2183-95. [PMID:21381763]