fluticasone propionate

Ligand id: 7080

Name: fluticasone propionate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 105.97
Molecular weight 500.18
XLogP 3.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Biggadike K, Angell RM, Burgess CM, Farrell RM, Hancock AP, Harker AJ, Irving WR, Ioannou C, Procopiou PA, Shaw RE et al.. (2000)
Selective plasma hydrolysis of glucocorticoid gamma-lactones and cyclic carbonates by the enzyme paraoxonase: an ideal plasma inactivation mechanism.
J. Med. Chem.43 (1): 19-21. [PMID:10633034]