cilostazol

Ligand id: 7148

Name: cilostazol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 81.93
Molecular weight 369.22
XLogP 3.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Maki T, Okamoto Y, Carare RO, Hase Y, Hattori Y, Hawkes CA, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda H et al.. (2014)
Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid.
Ann Clin Transl Neurol1 (8): 519-33. [PMID:25356424]
2. Sudo T, Tachibana K, Toga K, Tochizawa S, Inoue Y, Kimura Y, Hidaka H. (2000)
Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity.
Biochem. Pharmacol.59 (4): 347-56. [PMID:10644042]