hydroxychloroquine

Ligand id: 7198

Name: hydroxychloroquine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 48.39
Molecular weight 335.18
XLogP 3.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Kawai T, Akira S. (2010)
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors.
Nat. Immunol.11 (5): 373-84. [PMID:20404851]
2. Lamphier M, Zheng W, Latz E, Spyvee M, Hansen H, Rose J, Genest M, Yang H, Shaffer C, Zhao Y et al.. (2014)
Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
Mol. Pharmacol.85 (3): 429-40. [PMID:24342772]