hydroxyzine

Ligand id: 7199

Name: hydroxyzine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 35.94
Molecular weight 374.18
XLogP 4.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Gillard M, Van Der Perren C, Moguilevsky N, Massingham R, Chatelain P. (2002)
Binding characteristics of cetirizine and levocetirizine to human H(1) histamine receptors: contribution of Lys(191) and Thr(194).
Mol. Pharmacol.61 (2): 391-9. [PMID:11809864]