nebivolol

Ligand id: 7246

Name: nebivolol

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: nebivolol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 70.95
Molecular weight 405.18
XLogP 3.15
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Pauwels PJ, Gommeren W, Van Lommen G, Janssen PA, Leysen JE. (1988)
The receptor binding profile of the new antihypertensive agent nebivolol and its stereoisomers compared with various beta-adrenergic blockers.
Mol. Pharmacol.34 (6): 843-51. [PMID:2462161]