promethazine

Ligand id: 7282

Name: promethazine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 31.78
Molecular weight 284.13
XLogP 4.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Ghoneim OM, Legere JA, Golbraikh A, Tropsha A, Booth RG. (2006)
Novel ligands for the human histamine H1 receptor: synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes.
Bioorg. Med. Chem.14 (19): 6640-58. [PMID:16782354]