tolazoline

Ligand id: 7310

Name: tolazoline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 24.39
Molecular weight 160.1
XLogP 3.13
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Jasper JR, Lesnick JD, Chang LK, Yamanishi SS, Chang TK, Hsu SAO, Daunt DA, Bonhaus DW, Eglen RM. (1998)
Ligand efficacy and potency at recombinant alpha 2 adrenergic receptors - Agonist-mediated [35S]GTPgammaS binding.
Biochem Pharmacol.55: 1035-1043. [PMID:9605427]
2. Teskin O, Uydeş-Dogan BS, Enç Y, Alp FI, Kaleli D, Keser S, Iyigün T, Bilgen F, Dagsali S, Ozdemir O. (2006)
Comparative effects of tolazoline and nitroprusside on human isolated radial artery.
Ann. Thorac. Surg.81 (1): 125-31. [PMID:16368348]