florbetapir

Ligand id: 7344

Name: florbetapir    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 52.61
Molecular weight 360.18
XLogP 4.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Cortes-Blanco A, Prieto-Yerro C, Martinez-Lazaro R, Zamora J, Jiménez-Huete A, Haberkamp M, Pohly J, Enzmann H, Zinserling J, Strassmann V et al.. (2014)
Florbetapir ((18)F) for brain amyloid positron emission tomography: Highlights on the European marketing approval.
Alzheimers Dement,  [Epub ahead of print]. [PMID:24418060]
2. Yu P, Cui M, Wang X, Zhang X, Li Z, Yang Y, Jia J, Zhang J, Ono M, Saji H et al.. (2012)
¹⁸F-labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques.
Eur J Med Chem57: 51-8. [PMID:23047223]