Ligand id: 7422

Name: dacomitinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 79.38
Molecular weight 469.17
XLogP 3.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Barf T, Kaptein A. (2012)
Irreversible protein kinase inhibitors: balancing the benefits and risks.
J. Med. Chem.55 (14): 6243-62. [PMID:22621397]