moclobemide

Ligand id: 7428

Name: moclobemide

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View more information in the IUPHAR Pharmacology Education Project: moclobemide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 41.57
Molecular weight 268.1
XLogP 1.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Fulton B, Benfield P. (1996)
Moclobemide. An update of its pharmacological properties and therapeutic use.
Drugs52 (3): 450-74. [PMID:8875133]
2. Jagrat M, Behera J, Yabanoglu S, Ercan A, Ucar G, Sinha BN, Sankaran V, Basu A, Jayaprakash V. (2011)
Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies.
Bioorg. Med. Chem. Lett.21 (14): 4296-300. [PMID:21680183]