BIC1

Ligand id: 7510

Name: BIC1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 92.55
Molecular weight 340.08
XLogP 5.56
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Ito T, Umehara T, Sasaki K, Nakamura Y, Nishino N, Terada T, Shirouzu M, Padmanabhan B, Yokoyama S, Ito A et al.. (2011)
Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors.
Chem. Biol.18 (4): 495-507. [PMID:21513886]