BzT-7

Ligand id: 7515

Name: BzT-7

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 33.95
Molecular weight 323.09
XLogP 5.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Filippakopoulos P, Picaud S, Fedorov O, Keller M, Wrobel M, Morgenstern O, Bracher F, Knapp S. (2012)
Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.
Bioorg. Med. Chem.20 (6): 1878-86. [PMID:22137933]