thiotepa

Ligand id: 7622

Name: thiotepa

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 50.93
Molecular weight 189.05
XLogP 0.76
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Maanen MJ, Smeets CJ, Beijnen JH. (2000)
Chemistry, pharmacology and pharmacokinetics of N,N',N" -triethylenethiophosphoramide (ThioTEPA).
Cancer Treat. Rev.26 (4): 257-68. [PMID:10913381]