blonanserin

Ligand id: 7670

Name: blonanserin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 19.37
Molecular weight 367.24
XLogP 6.03
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Ochi T, Sakamoto M, Minamida A, Suzuki K, Ueda T, Une T, Toda H, Matsumoto K, Terauchi Y. (2005)
Syntheses and properties of the major hydroxy metabolites in humans of blonanserin AD-5423, a novel antipsychotic agent.
Bioorg. Med. Chem. Lett.15 (4): 1055-9. [PMID:15686911]
2. Oka M, Noda Y, Ochi Y, Furukawa K, Une T, Kurumiya S, Hino K, Karasawa T. (1993)
Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties.
J. Pharmacol. Exp. Ther.264 (1): 158-65. [PMID:8093723]