brexpiprazole

Ligand id: 7672

Name: brexpiprazole

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 73.05
Molecular weight 433.18
XLogP 4.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Citrome L. (2015)
Brexpiprazole for schizophrenia and as adjunct for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antipsychotic - what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?.
Int. J. Clin. Pract.,  [Epub ahead of print]. [PMID:26250067]
2. Maeda K, Sugino H, Akazawa H, Amada N, Shimada J, Futamura T, Yamashita H, Ito N, McQuade RD, Mørk A et al.. (2014)
Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.
J. Pharmacol. Exp. Ther.350 (3): 589-604. [PMID:24947465]