AZD7762

Ligand id: 7713

Name: AZD7762

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 124.49
Molecular weight 362.12
XLogP 2.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Oza V, Ashwell S, Almeida L, Brassil P, Breed J, Deng C, Gero T, Grondine M, Horn C, Ioannidis S et al.. (2012)
Discovery of checkpoint kinase inhibitor (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by structure-based design and optimization of thiophenecarboxamide ureas.
J. Med. Chem.55 (11): 5130-42. [PMID:22551018]