AZD1080

Ligand id: 7819

Name: AZD1080

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 77.39
Molecular weight 334.14
XLogP 1.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Georgievska B, Sandin J, Doherty J, Mörtberg A, Neelissen J, Andersson A, Gruber S, Nilsson Y, Schött P, Arvidsson PI et al.. (2013)
AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
J. Neurochem.125 (3): 446-56. [PMID:23410232]