AT-9283

Ligand id: 7949

Name: AT-9283

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 102.38
Molecular weight 381.19
XLogP -0.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Howard S, Berdini V, Boulstridge JA, Carr MG, Cross DM, Curry J, Devine LA, Early TR, Fazal L, Gill AL et al.. (2009)
Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity.
J. Med. Chem.52 (2): 379-88. [PMID:19143567]