Synonyms: SAR-245409 | SAR245409 | XL765
Compound class:
Synthetic organic
Comment: Voxtalisib is an orally bioavailable small molecule inhibitor of phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinases in the PI3K/mTOR signaling pathway, with potential antineoplastic activity [1].
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References |
1. Garcia-Echeverria C, Sellers WR. (2008)
Drug discovery approaches targeting the PI3K/Akt pathway in cancer. Oncogene, 27 (41): 5511-26. [PMID:18794885] |