Ligand id: 7975

Name: BPH-675

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 6
Rotatable bonds 8
Topological polar surface area 209.46
Molecular weight 563.06
XLogP 4.52
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y et al.. (2007)
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.
Proc. Natl. Acad. Sci. U.S.A., 104 (24): 10022-7. [PMID:17535895]