Compound class:
Synthetic organic
Comment: This compound is as allosteric inhibitor of oncogenic KRASG12C [1].
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References |
1. Ostrem JM, Peters U, Sos ML, Wells JA, Shokat KM. (2013)
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503 (7477): 548-51. [PMID:24256730] |