AZD6482

Ligand id: 8059

Name: AZD6482

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 82.11
Molecular weight 408.18
XLogP 2.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Nylander S, Kull B, Björkman JA, Ulvinge JC, Oakes N, Emanuelsson BM, Andersson M, Skärby T, Inghardt T, Fjellström O et al.. (2012)
Human target validation of phosphoinositide 3-kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor.
J. Thromb. Haemost.10 (10): 2127-36. [PMID:22906130]