CGI1746

Ligand id: 8066

Name: CGI1746

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 90.98
Molecular weight 579.28
XLogP 7.15
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Di Paolo JA, Huang T, Balazs M, Barbosa J, Barck KH, Bravo BJ, Carano RA, Darrow J, Davies DR, DeForge LE et al.. (2011)
Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.
Nat. Chem. Biol.7 (1): 41-50. [PMID:21113169]