CP-673451

Ligand id: 8069

Name: CP-673451

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 78.43
Molecular weight 417.22
XLogP 3.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Roberts WG, Whalen PM, Soderstrom E, Moraski G, Lyssikatos JP, Wang HF, Cooper B, Baker DA, Savage D, Dalvie D et al.. (2005)
Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451.
Cancer Res.65 (3): 957-66. [PMID:15705896]