compound 2c [PMID: 24900538]

Ligand id: 8138

Name: compound 2c [PMID: 24900538]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 93.54
Molecular weight 381.17
XLogP 4.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Wang T, Lamb ML, Block MH, Davies AM, Han Y, Hoffmann E, Ioannidis S, Josey JA, Liu ZY, Lyne PD et al.. (2012)
Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA Inhibitors.
ACS Med Chem Lett3 (9): 705-9. [PMID:24900538]