compound 23 [PMID: 17600705]

Ligand id: 8146

Name: compound 23 [PMID: 17600705]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 138.61
Molecular weight 371.11
XLogP 2.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Bamborough P, Angell RM, Bhamra I, Brown D, Bull J, Christopher JA, Cooper AW, Fazal LH, Giordano I, Hind L et al.. (2007)
N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: indazoles as phenol isosteres with improved pharmacokinetics.
Bioorg. Med. Chem. Lett.17 (15): 4363-8. [PMID:17600705]