compound 13a [PMID: 23639540]

Ligand id: 8155

Name: compound 13a [PMID: 23639540]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 71.34
Molecular weight 346.15
XLogP 1.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Engers DW, Frist AY, Lindsley CW, Hong CC, Hopkins CR. (2013)
Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe.
Bioorg. Med. Chem. Lett.23 (11): 3248-52. [PMID:23639540]