compound 17 [PMID: 23642479]

Ligand id: 8161

Name: compound 17 [PMID: 23642479]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 56.27
Molecular weight 373.04
XLogP 4.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Coombs TC, Tanega C, Shen M, Wang JL, Auld DS, Gerritz SW, Schoenen FJ, Thomas CJ, AubĂ© J. (2013)
Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315.
Bioorg. Med. Chem. Lett.23 (12): 3654-61. [PMID:23642479]