compound 8h [PMID: 22765894]

Ligand id: 8175

Name: compound 8h [PMID: 22765894]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 73.05
Molecular weight 447.18
XLogP 3.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Kim MH, Tsuhako AL, Co EW, Aftab DT, Bentzien F, Chen J, Cheng W, Engst S, Goon L, Klein RR et al.. (2012)
The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors.
Bioorg. Med. Chem. Lett.22 (15): 4979-85. [PMID:22765894]