compound 18 [PMID: 20873740]

Ligand id: 8191

Name: compound 18 [PMID: 20873740]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 110.68
Molecular weight 279.11
XLogP 2.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Menichincheri M, Albanese C, Alli C, Ballinari D, Bargiotti A, Caldarelli M, Ciavolella A, Cirla A, Colombo M, Colotta F et al.. (2010)
Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding.
J. Med. Chem.53 (20): 7296-315. [PMID:20873740]