amg-1

Ligand id: 8227

Name: amg-1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 131.29
Molecular weight 424.07
XLogP 5.26
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Meininger D, Zalameda L, Liu Y, Stepan LP, Borges L, McCarter JD, Sutherland CL. (2011)
Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors.
Biochim. Biophys. Acta1814 (12): 1947-54. [PMID:21835273]