Ligand id: 8227

Name: amg-1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 131.29
Molecular weight 424.07
XLogP 5.26
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Meininger D, Zalameda L, Liu Y, Stepan LP, Borges L, McCarter JD, Sutherland CL. (2011)
Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors.
Biochim. Biophys. Acta1814 (12): 1947-54. [PMID:21835273]