ABT-670

Ligand id: 8439

Name: ABT-670

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 59.28
Molecular weight 325.18
XLogP 4.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Patel MV, Kolasa T, Mortell K, Matulenko MA, Hakeem AA, Rohde JJ, Nelson SL, Cowart MD, Nakane M, Miller LN et al.. (2006)
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.
J. Med. Chem.49 (25): 7450-65. [PMID:17149874]