compound 24dd [PMID: 20684603]

Ligand id: 8550

Name: compound 24dd [PMID: 20684603]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 98.2
Molecular weight 454.11
XLogP 3.62
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Meng W, Brigance RP, Chao HJ, Fura A, Harrity T, Marcinkeviciene J, O'Connor SP, Tamura JK, Xie D, Zhang Y et al.. (2010)
Discovery of 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors.
J. Med. Chem.53 (15): 5620-8. [PMID:20684603]