ARI-3099

Ligand id: 8563

Name: ARI-3099

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 102.76
Molecular weight 291.14
XLogP -0.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014)
A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity.
Nat. Chem. Biol.10 (8): 656-63. [PMID:24997602]
2. Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, Wu W, Wu Y, Zhou Y, Sudmeier JL, Sanford DG et al.. (2013)
Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.
J. Med. Chem.56 (9): 3467-77. [PMID:23594271]