example 8 [WO1999033801A1]

Ligand id: 8581

Name: example 8 [WO1999033801A1]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 75.43
Molecular weight 347.13
XLogP 2.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Chen Y, Ganellin CR, Rose C, Samad S, Schwartz J-C, Vargas F, Zhao L. (1999)
Tripeptidyl peptidase inhibitors.
Patent number: WO1999033801 A1. Assignee: Inst Nat Sante Rech Med, Chen Y, Ganellin CR, Rose C, Samad S, Schwartz J-C, Vargas F, Zhao L. Priority date: 23/12/1998. Publication date: 08/07/1999.
2. Rockel B, Kopec KO, Lupas AN, Baumeister W. (2012)
Structure and function of tripeptidyl peptidase II, a giant cytosolic protease.
Biochim. Biophys. Acta1824 (1): 237-45. [PMID:21771670]