Alexa-488-telenzepine

Ligand id: 8600

Name: Alexa-488-telenzepine  

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 4
Rotatable bonds 20
Topological polar surface area 352.56
Molecular weight 1025.28
XLogP 6.49
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

References
1. Hern JA, Baig AH, Mashanov GI, Birdsall B, Corrie JE, Lazareno S, Molloy JE, Birdsall NJ. (2010)
Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules.
Proc. Natl. Acad. Sci. U.S.A.107 (6): 2693-8. [PMID:20133736]
2. Nenasheva TA, Neary M, Mashanov GI, Birdsall NJ, Breckenridge RA, Molloy JE. (2013)
Abundance, distribution, mobility and oligomeric state of M₂ muscarinic acetylcholine receptors in live cardiac muscle.
J. Mol. Cell. Cardiol.57: 129-36. [PMID:23357106]