compound 4g [PMID: 22595175]

Ligand id: 8626

Name: compound 4g [PMID: 22595175]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 72.91
Molecular weight 263.08
XLogP 1.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Santana AB, Lucas SD, Gonçalves LM, Correia HF, Cardote TA, Guedes RC, Iley J, Moreira R. (2012)
N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases.
Bioorg. Med. Chem. Lett.22 (12): 3993-7. [PMID:22595175]