|
Compound class:
Peptide or derivative
Comment: YJ34 is a peptide inhibitor of the regulator of G-protein signaling 4 (RGS4) protein [1].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
|
1. Jin Y, Zhong H, Omnaas JR, Neubig RR, Mosberg HI. (2004)
Structure-based design, synthesis, and pharmacologic evaluation of peptide RGS4 inhibitors. J Pept Res, 63 (2): 141-6. [PMID:15009535] |
|
2. Roof RA, Jin Y, Roman DL, Sunahara RK, Ishii M, Mosberg HI, Neubig RR. (2006)
Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins. Chem Biol Drug Des, 67 (4): 266-74. [PMID:16629824] |
