dexloxiglumide

Ligand id: 889

Name: dexloxiglumide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 16
Topological polar surface area 95.94
Molecular weight 460.15
XLogP 3.42
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Morton MF, Barrett TD, Yan W, Freedman JM, Lagaud G, Prendergast CE, Moreno V, Pyati J, Figueroa K, Li L, Wu X, Rizzolio M, Breitenbucher JG, McClure K, Shankley NP. (2007)
3-[5-(3,4-Dichloro-phenyl)-1-(4-methoxy-phenyl) -1H-pyrazol-3-yl]-2-m-tolyl-propionate (JNJ-17156516), a novel, potent, and selective cholecystokinin 1 receptor antagonist: in vitro and in vivo pharmacological comparison with dexloxiglumide.
J Pharmacol Exp Ther323: 562-569. [PMID:17684117]