pyridostigmine

Ligand id: 8994

Name: pyridostigmine

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View more information in the IUPHAR Pharmacology Education Project: pyridostigmine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 33.42
Molecular weight 181.1
XLogP 1.09
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Yu QS, Holloway HW, Luo W, Lahiri DK, Brossi A, Greig NH. (2010)
Long-acting anticholinesterases for myasthenia gravis: synthesis and activities of quaternary phenylcarbamates of neostigmine, pyridostigmine and physostigmine.
Bioorg. Med. Chem.18 (13): 4687-93. [PMID:20627738]