eCF506

Ligand id: 9186

Name: eCF506

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 123.66
Molecular weight 510.31
XLogP 2.13
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Fraser C, Dawson JC, Dowling R, Houston DR, Weiss JT, Munro AF, Muir M, Harrington L, Webster SP, Frame MC et al.. (2016)
Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase.
J. Med. Chem.,  [Epub ahead of print]. [PMID:27115835]